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Vanda Pharmaceuticals
Vanda Pharmaceuticals
(VNDA)
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Therapeutic Areas:
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Classification:
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Include Generics:
Trade Name
Drug Name
Approved
Patent Expires
Indication
Fanapt
Iloperidone
2009-05-06
2025-2031
Schizophrenia
,
Schizophrenia spectrum and other psychotic disorders
Hetlioz
Tasimelteon
2014-01-31
2033-2041
Circadian rhythm sleep disorders
Ponvory
Ponesimod
2021-03-18
2024-2035
Relapsing-remitting multiple sclerosis
Clinical Trials
Therapeutic Areas:
All
Classification:
All
Approval:
All
Status:
All
Phases:
All
Drug Name
Phase 1
Phase 2
Phase 3
Phase 4
Indication
Tasimelteon
healthy volunteers/patients
,
renal insufficiency
,
liver diseases
,
hepatic insufficiency
,
rem sleep behavior disorder
,
mental disorders
,
sleep initiation and maintenance disorders
,
smith-magenis syndrome
,
autism spectrum disorder
,
chronobiology disorders
,
jet lag syndrome
,
dyssomnias
,
parasomnias
,
depression
,
major depressive disorder
,
depressive disorder
,
syndrome
,
circadian rhythm
,
nervous system diseases
,
autistic disorder
,
pervasive child development disorders
,
sleep wake disorders
,
circadian rhythm sleep disorders
Iloperidone
liver diseases
,
hepatic insufficiency
,
therapeutic equivalency
,
mental disorders
,
post-traumatic stress disorders
,
traumatic stress disorders
,
anhedonia
,
parkinson disease
,
recurrence
,
schizophrenia
,
bipolar disorder
,
psychotic disorders
,
healthy volunteers/patients
,
depression
,
major depressive disorder
,
depressive disorder
,
weight gain
,
stroke
,
drug-related side effects and adverse reactions
,
drug interactions
,
glucose metabolism disorders
,
insulin resistance
,
metabolic syndrome
Tradipitant
pruritus
,
healthy volunteers/patients
,
alcoholism
,
anxiety disorders
,
social phobia
,
dyspepsia
,
obesity
,
vomiting
,
nausea
,
gastroparesis
,
motion sickness
,
atopic dermatitis
,
eczema
,
dermatitis
,
infections
,
coronavirus infections
,
communicable diseases
Aspartame
healthy volunteers/patients
,
laron syndrome
,
pituitary dwarfism
,
leukemia
,
myelodysplastic syndromes
,
myeloid leukemia acute
,
megakaryoblastic leukemia acute
,
monocytic leukemia acute
,
myelomonocytic leukemia acute
,
myeloid leukemia
,
erythroblastic leukemia acute
,
neoplasms
,
dyspnea
,
asthma
,
chronic obstructive pulmonary disease
,
lung diseases
,
obstructive lung diseases
,
inflammation
Bevifimod
healthy volunteers/patients
,
neurofibroma
,
chronic renal insufficiency
,
knee osteoarthritis
,
osteoarthritis
,
liver diseases
,
hepatic insufficiency
,
brca1 genes
,
telomeric repeat binding protein 2
,
oncogenes
,
plexiform neurofibroma
,
therapeutic equivalency
,
pharmacokinetics
,
biological availability
,
coronary disease
,
coronary artery disease
,
myocardial ischemia
,
uveal neoplasms
,
neuroblastoma
,
osteosarcoma
,
rhabdomyosarcoma
,
gliosarcoma
,
liver failure
,
head and neck neoplasms
,
non-hodgkin lymphoma
,
prostatic neoplasms
,
squamous cell neoplasms
,
pancreatic neoplasms
,
endometrial neoplasms
,
multiple myeloma
,
urinary bladder neoplasms
,
melanoma
,
neurofibromatosis 1
,
neurofibromatoses
,
asthma
,
chronic obstructive pulmonary disease
,
esophageal neoplasms
,
serous cystadenocarcinoma
,
colonic neoplasms
,
hematologic neoplasms
,
type 2 diabetes mellitus
,
diabetes mellitus
,
obstructive lung diseases
,
follicular lymphoma
,
uterine neoplasms
,
carcinosarcoma
,
mullerian mixed tumor
,
glioma
,
waldenstrom macroglobulinemia
,
sarcoma
,
uterine cervical neoplasms
,
cardiovascular diseases
,
peritoneal neoplasms
,
leiomyosarcoma
,
hereditary breast and ovarian cancer syndrome
,
pancreatic ductal carcinoma
,
small cell carcinoma
,
b-cell lymphoma marginal zone
,
neurofibrosarcoma
,
nerve sheath neoplasms
,
respiratory aspiration
,
lung diseases
,
urethral neoplasms
,
ureteral neoplasms
,
pelvic neoplasms
,
castration-resistant prostatic neoplasms
,
aggression
,
precursor cell lymphoblastic leukemia-lymphoma
,
nasopharyngeal carcinoma
,
nasopharyngeal neoplasms
,
epstein-barr virus infections
,
oropharyngeal neoplasms
,
peripheral nervous system diseases
,
malignant mesothelioma
,
mesothelioma
,
adrenocortical carcinoma
,
adenocarcinoma of lung
,
salivary gland neoplasms
,
central nervous system neoplasms
,
germ cell and embryonal neoplasms
,
skin neoplasms
,
pleural effusion
,
malignant pleural effusion
,
thyroid neoplasms
,
neoplasms
,
breast neoplasms
,
carcinoma
,
ovarian neoplasms
,
colorectal neoplasms
,
small cell lung carcinoma
,
large b-cell lymphoma diffuse
,
adenocarcinoma
,
liver neoplasms
,
recurrence
,
b-cell lymphoma
,
squamous cell carcinoma
,
renal cell carcinoma
,
hepatocellular carcinoma
,
ovarian epithelial carcinoma
,
glioblastoma
,
covid-19
,
stomach neoplasms
,
triple negative breast neoplasms
,
fallopian tube neoplasms
,
biliary tract neoplasms
,
kidney neoplasms
,
neoplasm metastasis
,
squamous cell carcinoma of head and neck
,
brain neoplasms
,
transitional cell carcinoma
,
urologic neoplasms
,
infections
,
communicable diseases
,
hypersensitivity
,
endometrioid carcinoma
,
mucinous cystadenocarcinoma
,
clear cell adenocarcinoma
,
acinar cell carcinoma
,
neoplasms by site
,
gastrointestinal stromal tumors
,
male breast neoplasms
,
non-small-cell lung carcinoma
,
lung neoplasms
,
lymphoma
,
b-cell chronic lymphocytic leukemia
,
leukemia
,
lymphoid leukemia
,
mantle-cell lymphoma
,
kidney diseases
,
hypertension
,
migraine disorders
,
headache
,
heart failure
,
hyperkalemia
,
inflammation
,
diagnosis
,
smoking
,
family relations
Corticorelin
obesity
,
respiratory insufficiency
,
rheumatoid arthritis
,
osteoporosis
,
bacterial infections
,
dementia
,
acute disease
,
colonic neoplasms
,
meningitis
,
sleep deprivation
,
hyperlipidemias
,
diabetic neuropathies
,
alzheimer disease
,
virus diseases
,
streptococcal infections
,
adrenal insufficiency
,
cocaine-related disorders
,
motor neuron disease
,
airway extubation
,
cellulitis
,
systemic lupus erythematosus
,
overweight
,
arthritis
,
epilepsy
,
factor xi deficiency
,
primary myelofibrosis
,
ebola hemorrhagic fever
,
marburg virus disease
,
metabolic bone diseases
,
amyotrophic lateral sclerosis
,
overactive urinary bladder
,
endometriosis
,
chronic cough
,
bacterial meningitis
,
neisseriaceae infections
,
staphylococcal skin infections
,
infectious skin diseases
,
porokeratosis
,
malformed nails
,
pachyonychia congenita
,
palmoplantar keratoderma
,
dialysis
,
colorectal neoplasms
,
cognitive dysfunction
,
lung neoplasms
,
retinal diseases
,
chronic disease
,
non-small-cell lung carcinoma
,
pure red-cell aplasia
,
sleep wake disorders
,
postoperative pain
,
myeloid leukemia
,
alcoholism
,
parasomnias
,
hemodiafiltration
,
liver diseases
,
carcinoma
,
irritable bowel syndrome
,
blood pressure
,
dyssomnias
,
ovarian neoplasms
,
immunosuppression therapy
,
heart disease risk factors
,
drug therapy
,
hypogonadism
,
pituitary neoplasms
,
amyloidosis
,
constipation
,
substance-related disorders
,
survivorship
,
myeloid leukemia acute
,
xerostomia
,
post-acute covid-19 syndrome
,
bcr-abl positive chronic myelogenous leukemia
,
chronic kidney disease-mineral and bone disorder
,
renal cell carcinoma
,
wasting syndrome
,
cachexia
,
deficiency diseases
,
squamous cell carcinoma
,
arthralgia
,
eunuchism
,
olfaction disorders
,
feeding behavior
,
post-traumatic stress disorders
,
traumatic stress disorders
,
premature birth
,
fasting
,
bone diseases
,
alcohol-related disorders
,
prediabetic state
,
chronic hepatitis b
,
systolic heart failure
,
reperfusion injury
,
squamous cell carcinoma of head and neck
,
myalgia
,
encephalomyelitis
,
esophageal neoplasms
,
weight loss
,
cardiovascular abnormalities
,
replacement arthroplasty knee
,
immunoglobulin light-chain amyloidosis
,
adenocarcinoma
,
end stage liver disease
,
acute-phase reaction
,
clinical deterioration
,
obsessive-compulsive disorder
,
compulsive personality disorder
,
pathologic dilatation
,
staphylococcus aureus
,
neoplasms
,
breast neoplasms
,
neoplasm metastasis
,
prostatic neoplasms
,
leukemia
,
thrombosis
,
fibrosis
,
sepsis
,
hyperplasia
,
stroke
,
chronic obstructive pulmonary disease
,
chronic pain
,
osteoarthritis
,
thromboembolism
,
brain neoplasms
,
brain edema
,
edema
,
lymphoma
,
fabry disease
,
pituitary acth hypersecretion
,
type 1 diabetes mellitus
,
chronic fatigue syndrome
,
iga glomerulonephritis
,
liver cirrhosis
,
recurrence
,
anxiety disorders
,
iron deficiencies
,
adrenocortical hyperfunction
,
emergencies
,
restless legs syndrome
,
lung diseases
,
hematologic neoplasms
,
calciphylaxis
,
staphylococcal infections
,
nephrosclerosis
,
hemorrhage
,
hemolysis
,
vascular access devices
,
disease progression
,
male breast neoplasms
,
acth-secreting pituitary adenoma
,
pulmonary hypertension
,
iron-deficiency anemia
,
congenital adrenal hyperplasia
,
adrenogenital syndrome
,
toxemia
,
uterine cervical neoplasms
,
psychomotor agitation
,
endocarditis
,
low back pain
,
back pain
,
second primary neoplasms
,
bone fractures
,
hodgkin disease
,
hypoalbuminemia
,
critical illness
,
affect
,
hip osteoarthritis
,
myelodysplastic syndromes
,
obstructive lung diseases
,
papilloma
,
hip fractures
,
hepacivirus
,
pharmacological phenomena
,
catheter-related infections
,
large b-cell lymphoma diffuse
,
vasculitis
,
anti-neutrophil cytoplasmic antibody-associated vasculitis
,
systemic inflammatory response syndrome
,
drug resistance
,
respiratory distress syndrome
,
acute lung injury
,
newborn respiratory distress syndrome
,
transient ischemic attack
,
peripheral catheterization
,
ileus
,
intestinal pseudo-obstruction
,
acidosis
,
radiotherapy
,
leukopenia
,
chinese traditional medicine
,
myeloproliferative disorders
,
precancerous conditions
,
myelodysplastic-myeloproliferative diseases
,
lymphoproliferative disorders
,
preleukemia
,
plasmacytoma
,
hemolytic-uremic syndrome
,
malignant hypertension
,
azotemia
,
hypertensive crisis
,
chronic kidney failure
,
kidney diseases
,
renal insufficiency
,
chronic renal insufficiency
,
fatigue
,
anemia
,
renal dialysis
,
diabetes mellitus
,
cardiovascular diseases
,
kidney transplantation
,
hypertension
,
healthy volunteers/patients
,
type 2 diabetes mellitus
,
inflammation
,
fistula
,
arteriovenous fistula
,
hyperphosphatemia
,
hyperparathyroidism
,
infections
,
hepatitis c
,
secondary hyperparathyroidism
,
hepatitis
,
pruritus
,
covid-19
,
heart failure
,
syndrome
,
acute kidney injury
,
chronic hepatitis c
,
hepatitis a
,
communicable diseases
,
depression
,
peritoneal dialysis
,
diabetic nephropathies
,
multiple myeloma
,
plasma cell neoplasms
,
vascular calcification
,
depressive disorder
,
calcinosis
,
hiv infections
,
insulin resistance
,
hepatitis b
,
hypotension
,
tuberculosis
,
coronary disease
,
atherosclerosis
,
renal replacement therapy
,
left ventricular hypertrophy
,
hypertrophy
,
vascular stiffness
,
bacteremia
,
chronic hepatitis
,
malnutrition
,
head and neck neoplasms
,
coronary artery disease
,
proteinuria
,
polycystic kidney diseases
,
neuralgia
,
myocardial ischemia
,
delayed graft function
,
graft rejection
,
pharmacokinetics
,
hypersensitivity
,
autosomal dominant polycystic kidney
,
ischemia
,
oxidative stress
,
pituitary diseases
,
latent tuberculosis
,
atrial fibrillation
,
hypercholesterolemia
,
dyslipidemias
,
arthrogryposis
,
hyperkalemia
,
acute coronary syndrome
,
renal hypertension
,
mental disorders
,
peritonitis
,
disorders of excessive somnolence
,
pathologic constriction
,
pain
,
periodontitis
,
heart transplantation
,
uremia
,
hyperuricemia
,
sleepiness
,
chronic periodontitis
,
hypopituitarism
,
brachial plexus block
,
metabolic diseases
,
phosphorus metabolism disorders
,
acquired immunodeficiency syndrome
,
coinfection
,
neuromuscular blockade
,
graft vs host disease
,
hiv
,
renovascular hypertension
,
renal artery obstruction
,
esophageal motility disorders
,
diffuse esophageal spasm
,
human influenza
,
hyperkinesis
,
attention deficit disorder with hyperactivity
,
prospective studies
,
single-blind method
,
hypothalamic diseases
,
hemophilia b
,
diabetes insipidus
,
neurogenic diabetes insipidus
,
social isolation
,
macular degeneration
,
wet macular degeneration
,
death
,
sleep apnea syndromes
,
apnea
,
exercise
,
major depressive disorder
,
wounds and injuries
,
peripheral arterial disease
,
heart diseases
,
obstructive sleep apnea
,
peripheral vascular diseases
,
hypoxia
,
cardiac arrhythmias
,
palliative care
,
decision making
,
anxiety
,
venous thromboembolism
,
myocardial infarction
,
infarction
,
sleep initiation and maintenance disorders
,
fever
,
sleep
,
non-alcoholic fatty liver disease
,
fatty liver
,
stomach neoplasms
,
laron syndrome
,
shock
,
decision support techniques
,
therapeutics
,
diabetic foot
,
arteriosclerosis
,
nursing care
,
pulmonary embolism
,
embolism
,
sudden death cardiac
,
water intoxication
,
congenital abnormalities
,
cushing syndrome
,
knee osteoarthritis
,
sarcopenia
,
inferior wall myocardial infarction
,
continuous ambulatory peritoneal dialysis
,
drug-related side effects and adverse reactions
,
crohn disease
,
chronobiology disorders
,
fallopian tube neoplasms
,
ovarian epithelial carcinoma
,
female genital neoplasms
,
acrodynia
,
medication adherence
,
vitamin d deficiency
,
pregnancy
,
hypoglycemia
,
taste disorders
,
diabetic angiopathies
,
diabetes complications
,
diabetic retinopathy
,
immunologic deficiency syndromes
,
multiple sclerosis
,
cystic fibrosis
,
inflammatory bowel diseases
,
psychotic disorders
,
paralysis
,
facies
,
immunologic monitoring
,
cross infection
,
pregnancy-induced hypertension
,
cardiogenic shock
,
mortality
,
dyspnea
,
carotid intima-media thickness
,
frailty
,
glioblastoma
,
radiculopathy
,
intervertebral disc displacement
,
nephritis
,
self efficacy
,
dwarfism
,
weight gain
,
food diet and nutrition
,
acupressure
,
cataract
,
diagnosis
,
asthma
,
vascular diseases
,
cardio-renal syndrome
,
germ cell and embryonal neoplasms
,
testicular neoplasms
,
venous thrombosis
,
respiratory tract infections
,
home hemodialysis
,
papillomavirus infections
,
aging
,
brain diseases
,
gastrointestinal neoplasms
,
abdominal aortic aneurysm
,
aneurysm
,
aortic aneurysm
,
thrombocytopenia
,
child mortality
,
catheters
,
metabolic syndrome
,
anesthesia
,
parathyroid diseases
,
drug hypersensitivity
,
circadian rhythm
,
morbid obesity
,
vascular graft occlusion
,
morals
,
ventricular remodeling
,
patient satisfaction
,
hot flashes
,
neck pain
,
foot and mouth disease hand
,
mouth diseases
,
foot-and-mouth disease
,
kidney neoplasms
,
hyperhomocysteinemia
,
protein-energy malnutrition
,
food preferences
,
sedentary behavior
,
keratoconus
,
glomerulonephritis
,
severe acute respiratory syndrome
,
respiratory aspiration
,
hypokalemia
,
gynecologic surgical procedures
,
pneumoperitoneum
,
altitude sickness
,
hyperthermia
,
exercise tolerance
,
endomyocardial fibrosis
,
parkinson disease
,
feasibility studies
,
dysbiosis
,
primary immunodeficiency diseases
,
common variable immunodeficiency
,
alcoholic fatty liver
,
chromosome aberrations
,
adenoma
,
otitis media
,
otitis
,
hematologic diseases
,
severe acute respiratory syndrome-related coronavirus
,
musculoskeletal diseases
,
pancreatitis
,
diarrhea
,
biliary liver cirrhosis
,
celiac disease
,
cholelithiasis
,
chronic pancreatitis
,
cholecystitis
,
exocrine pancreatic insufficiency
,
gastritis
,
pancreatic cyst
,
schizophrenia
,
schizophrenia spectrum and other psychotic disorders
,
status epilepticus
,
facial paralysis
,
bell palsy
,
dyspepsia
,
wound infection
,
leg ulcer
,
prostatic hyperplasia
,
addictive behavior
,
healthy diet
,
physical fitness
,
pre-eclampsia
,
eclampsia
,
cell transplantation
,
out-of-hospital cardiac arrest
,
sudden death
,
blood coagulation disorders
,
hemostatic disorders
,
bipolar disorder
,
vascular remodeling
,
prolapse
,
muscular diseases
,
self care
,
lower urinary tract symptoms
,
electric stimulation
,
skin diseases
,
dental implants
,
nociceptive pain
,
central nervous system sensitization
,
systemic scleroderma
,
diffuse scleroderma
,
sclerosis
,
echocardiography
,
asymptomatic diseases
,
gastrointestinal hemorrhage
,
communication
,
sars-cov-2
,
child development
,
neurodevelopmental disorders
,
ataxia
,
cerebellar ataxia
,
castration-resistant prostatic neoplasms
,
diphtheria
,
meningococcal meningitis
,
acne vulgaris
,
urologic neoplasms
,
hematuria
,
kwashiorkor
,
tachycardia
,
patient compliance
,
glioma
,
rehabilitation
,
hyperalgesia
,
mean platelet volume
,
femoral neck fractures
,
osteonecrosis
,
necrosis
,
patient participation
,
cardiorespiratory fitness
,
myocardial stunning
,
pelvic floor disorders
,
familial hypophosphatemic rickets
,
hypophosphatemic rickets
,
rickets
,
intrauterine devices
,
trigeminal neuralgia
,
blood volume
,
eye diseases
,
hepatectomy
,
hemostasis
,
mesenchymal stem cell transplantation
,
chronic limb-threatening ischemia
,
low-level light therapy
,
body weight
,
intermittent claudication
,
brain injuries
,
chronic brain injury
,
astigmatism
,
intraocular pressure
,
retinal detachment
,
vitreous detachment
,
myopia
,
pseudophakia
,
dissociative disorders
,
basal cell carcinoma
,
skin neoplasms
,
social behavior
,
cerebrovascular disorders
,
dental caries
,
cognition disorders
,
upper extremity deep vein thrombosis
,
pulmonary vein stenosis
,
central venous catheterization
,
intestinal diseases
,
pneumonia
,
urinary tract infections
,
osteomyelitis
,
abscess
,
enteritis
,
dehydration
,
gastroenteritis
,
malaria
,
hematopoietic stem cell transplantation
,
light
,
aortic valve stenosis
,
turner syndrome
,
gonadal dysgenesis
,
lung transplantation
,
cardiac surgical procedures
,
resistance training
,
transplantation
,
organ transplantation
,
immunocompromised host
,
emission-computed tomography single-photon
,
radioisotope diagnostic techniques
,
genetic predisposition to disease
,
lipodystrophy
,
myoma
,
essential hypertension
,
cleft lip
,
cleft palate
,
maxillofacial abnormalities
,
craniofacial abnormalities
,
blood platelet disorders
,
aids-associated nephropathy
,
failure to thrive
,
addison disease
,
vitamin k deficiency
,
congenital heart defects
,
hospitalization
,
vaccination
,
dengue
,
mental health
,
sexuality
,
healthy aging
,
root canal obturation
,
hernia
,
melanoma
,
glucagonoma
,
aortic diseases
,
nasal polyps
,
eosinophilia
,
polyps
,
pulmonary eosinophilia
,
hypocalcemia
,
myositis
,
glycogen storage disease type ii
,
muscular atrophy
,
spinal muscular atrophy
,
inclusion body myositis
,
spinal muscular atrophies of childhood
,
atopic dermatitis
,
dermatitis
,
mitochondrial diseases
,
patient reported outcome measures
,
analgesia
,
meniere disease
,
psychosocial functioning
,
extracorporeal membrane oxygenation
,
acute pain
,
rotator cuff injuries
,
aortic dissection
,
vascular malformations
,
urologic diseases
,
arteriovenous malformations
,
vascular fistula
,
microbial drug resistance
,
cardiomyopathies
,
multiple organ failure
,
only child
,
bariatric surgery
,
bacterial endocarditis
,
hemophilia a
,
tendinopathy
,
foot ulcer
,
syncope
,
unconsciousness
,
muscle relaxation
,
blood transfusion
,
precursor cell lymphoblastic leukemia-lymphoma
,
hepatorenal syndrome
,
dna repair-deficiency disorders
,
xeroderma pigmentosum
,
trichothiodystrophy syndromes
,
ichthyosis
,
cockayne syndrome
,
musculoskeletal abnormalities
,
drug overdose
,
recreational drug use
,
hemorrhoids
,
rh isoimmunization
,
fetal distress
,
plantar fasciitis
,
fasciitis
,
diet therapy
,
time
,
nephrotic syndrome
,
nephrosis
,
rectal neoplasms
,
caregiver burden
,
pancreatic neoplasms
,
cytomegalovirus infections
,
cytomegalovirus
,
spinal cord injuries
,
stevens-johnson syndrome
,
hyponatremia
,
peripheral nervous system diseases
,
nutritional support
,
thyroiditis
,
subacute thyroiditis
,
thyrotoxicosis
,
uterine cervical dysplasia
,
ciliopathies
,
muscle strength dynamometer
,
prehypertension
,
endovascular procedures
,
lupus nephritis
,
cerebral palsy
Mydfrin
healthy volunteers/patients
Benoxyl
actinic keratosis
,
keratosis
,
acne vulgaris
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